The Value-Driven Laboratory Reticulocyte Hemoglobin Content (RET-He): A Parameter with Well-Established Clinical Value Sysmex America White Paper
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Diagnosis of Iron Deficiency and Iron Deficiency Anemia with Reticulocyte Hemoglobin Content among Children Aged 6-18 Years
Background: Iron deficiency (ID) is the most common micronutrient deficiency in the world. If left untreated, ID will lead to iron deficiency anemia (IDA) and other irreversible consequences. The American Academy of Pediatrics recommended reticulocyte hemoglobin content (Ret-He) as an alternative laboratory examination to screen and detect ID. We aimed to compare Ret-He with other laboratory pa...
متن کاملReticulocyte hemoglobin equivalent (Ret He) and assessment of iron-deficient states
Direct measurement of the reticulocyte hemoglobin content provides useful information for the diagnosis and treatment of iron-deficient states. We have examined direct measurements of reticulocyte and red cell hemoglobin content on the Sysmex XE 2100 (Ret He and RBC He respectively) and the Bayer ADVIA 2120 (CHr and CH respectively) analyzers. Good agreement was found between Ret He and CHr (Y ...
متن کاملPotential utility of the new Sysmex XE 5000 red blood cell extended parameters in the study of disorders of iron metabolism.
BACKGROUND New erythrocyte parameters are reported by the Sysmex XE 5000 analyzer. This instrument measures the hemoglobin (Hb) content of individual red cells, calculates the percentage of hypochromic red cells (%Hypo He) and the percentage of hyperchromic red cells (%Hyper He) and quantifies the proportion of marginally sized erythrocytes (%Micro R and %Macro R). The goals of the study were t...
متن کاملClinical utility of the new Sysmex XE 2100 parameter - reticulocyte hemoglobin equivalent - in the diagnosis of anemia.
Our aim was to establish the reference values of the new parameter reticulocyte hemoglobin equivalent (RET-He) and to investigate its role in differentiating between iron deficiency anemia and anemia of chronic diseases. We found that RET-He was useful for diagnosing iron deficiency anemia. A cut-off point of 25 pg provided a specificity of 0.81 and a sensitivity of 0.76.
متن کاملDiagnosis of iron deficiency in patients undergoing hemodialysis.
To diagnose iron deficiency in patients undergoing hemodialysis, the percentage of hypochromic RBCs (with cellular hemoglobin concentration <280 g/L [HYPO%]) and mean reticulocyte hemoglobin content (CHret) provided by the Siemens ADVIA 120 and 2120 analyzers (Siemens Diagnostic Solutions, Tarrytown, NY) were proposed as alternatives to biochemical tests. Sysmex, with its XE-5000 analyzer (Sysm...
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